EFTA00284062

Harvesting Nature's Intelligence EFTA00284062 Developing forces in the ecosystem Consumers want food products to be a trusted source of health Plants are a vast and still untapped source of natural solutions Brightseed discovers compelling natural solutions with unprecedented speed 2 • brightseed EFTA00284063 Nature has always held the solution Universe of plant compounds More than 99.9% of plant compounds have yet to be discovered I or ,,;,. •s , • ‘Ibi v ' • ;,.= r • i...;;... , ' \ •‘)..L:. 10 000' '' 5 ... ...,.... - (-rN4A,_ tow e,' % .,...0.1•1 ., --"1 '.. 4‘":;. . '4;4; 0 . .:-Al* •, I's ‘, n ...‘<;.. ' •'•,,, , , • , V , . 1.. Known plant compound's --,...-1.-_: ,,•e:'-",'4, '!'-:;if''..-- .14 "S ,, ' 3 brightseed EFTA00284064 Brightseed unleashes nature's intelligence in food Brightseed's discoveries transform today's food CPG products into a scientifically proven source of health By restoring the central role of plants and their healthful compounds in nutrition, we can reconnect every person to the goodness in,the foods they eat 4 brightseed EFTA00284065 Brightseed built ForagerTM, nature's discovery engine ▪ Brightseed created Forager, a computational intelligence that understands nature more profoundly than human intelligence • Forager is fueled by Brightseed's growing proprietary data on the world's plants and deep knowledge of human biology • Forager interrogates and learns natural phenomena with unprecedented speed and scale, discovering natural compounds that solve unmet human problems 5 brightseed EFTA00284066 We find authentic sources of health compounds, faster Plant compound space Human metabolism • -jr • • • amino acid If; _ • • • • carbohydrate T •• 4444. • .•%. . •• • • .. . • cofactor • . • fatty acid . ••• • . . •• • • •• .• • • hot mone • •. • . • . . ••• 4. 6 . 1 • . • s . lipid nucleotide • •• • • % • • • 0 • • r. • . . •• • • .. t • • secondary metabolite 00 • • vitamin . % . e•• •,.. • . • • • ... • •'• • : •,, c Alt._ _• : • % • • : •• • • . • •• • •• • . 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' 7 g k ' Ai z''. * ii ",_ k i lt( •(.., 4 • ;-'' ‘ ‘1 • 0 , .- • 4p,- • ., ..„-•✓ • i . , ...•0 . .4. . , , It Ij , c • - .. firP*0' r—$ .' 1 5 'ir r. .Tio ir „.., .._.c.., ..1:s ,.., , , . . -;-:4 -, 1., `.:l' , .. . a, —ct 4 k.'i:;- /i : ‘!:. •‘.$' ' (I'04 . , - lit , • .., 40 ..,t‘i • ' s... ,., . 5 , 4c. . .i ,. • :.; -4 , !' _ .-J o. - i. 1 • Today's diet impairs our normal metabolic regulation, '-'..: ,7A ., 7--•rpo 1P,,rilio• •..ir ..„..,,,,,,•-- exposing us to the dangers of chronic illness such as :,,Iin.,' , • , ,, ,.v. • 4... ......i ...",. . -, • ii .,, • I - p•P' "--,;;;-*, -41-iir.:*. ., , k 4 ; ,- •-- ‹-;• -. '''''''`,,.. .. . ,,, - ' - ' ,._,r. ''.1. , ...b • ••• ',.4 '. • Itr.; 1 11, . ...., C4 .. *.t cardiovascular disease, diabetes, and liver disease ',L -'..-, ' r. • , l a' •:2.14.b ,„ ,t. Ira, 1 .., ... ..:, . ; • -....- ": ( ; 4: i. i ., ' 4 • ,..,.. Jr. . ,s,,,, : .7 :.,. ..,....1 • V -- ,a73D, V : . r •L•, ' ', • ...1 . i r, ', p op ,i, ..; • Magellan is a natural plant compound that boosts .\ 44: V . 4*... \ •,.. C.'. ., ‘.1,-• -; e '.. - _dr ., .. :.• A ! . . 1! - • . ,,,, .--.•.- ..• ..,i ,) ; : -, . - 71-,?4 A - the body's natural ability to regulate its metabolism • l',.,c ,, ,,,a ...-..;:,%,.,... :.- _.9:_ . ,:....,.....,,.. . 4, ,*4,., A,,, r4)• -0:0, - -. ... I• PA 'It .',,..* -. - e'..e, ,.t4 . ;4-.‘ . - .--,.. -4.''' '4' ',I. ' et-'. - • - 4, : `'2, 14--`, ' • V ...! • Magellan works through a clinically proven I: . 414 I. \ "i,, 1 . :t ,e'l % I ,, • 41,.....t t,i..? , 4, .!, mechanism of action, allowing the body to counter . 4 1 k. . . .... 7 ' ' tA cki ;,: ,' •544r7r,-, ', .'_,:it•!.oria :tjj *-;),, I. s -, ..„ pp.:7 ''-',,e, . .'k- ,...!'•!.% 1' l' _""•..-gz , t .',7, 1.=.*4-- #•* t ''' '' .t4-a % /C Fr i . - the adverse effects of modern food 4.,..) , a. - i_ r -, .v, il s I.' - - r.- t • e .. ..,-- ., . _ ,, I tt..•• lA , %ft - s ' . a, 6. '3- . • i. fs'! tt ,, ,, , Patents are pending on composition, methods, and - • 4 — ' *47 . 51.1. • _ . ,., 4,,-e . , ,.. .14-4 g ? 71 , ‘''')., 41- , &A' , ,„in - 4,• :-tip • .--r _ • ,,..-.• et, , . • y, 0— -; • , • ' process -, . ,..._,_ , • ‘,-, .04 v,,, .4,,, • 04 4 7* , two,. • - 1 ..t e ' ill' : 1‘. 41 - . 0 A ' A . • ..••,, 1 -, 4 .- . ,.. • ••,- --". It ti i P._ ;4' : • "I it. . 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YPPL'Nv:-. ,,11,1,z-jb:... *a .,.,14 .• ,1,. ;). t.‘ . 7 brightseed EFTA00284068 Magellan benefits reconnect consumers with brands "Naturally clears harmful fats" "Plant-powered body regulator" "Awaken your body's natural restorative powers" 8 % brightseed EFTA00284069 Why partner with Brightseed Offer proven health benefits Rapidly transform strategy to product Magellan Forager - Embed Magellan as a plant bioactive - Deliver plant-based solutions for in food, beverage or supplements strategically relevant health benefits in with category exclusivity your product portfolio - Provide consumers with purpose - Unlock the intrinsic health benefits of driven consumption, authentically your existing supply chain , 9 brightseed EFTA00284070 Accomplished management team Jim Flatt, PhD Sofia Elizondo, MBA Co-founder and CEO Co-founder and COO Biosciences leader with track record of translating Business leader with a track record of business model breakthrough discoveries and leading-edge technology innovation working with consumer goods, into commercially successful products, including pharmaceutical and technology companies. Former nutritional lipids at Martek Biosciences, renewable researcher at the BCG Henderson Institute and advisor products at Synthetic Genomics, renewable biofuels at to the United Nations. Launched, grew and managed Mascoma and food technology at Hampton Creek. MIT multi-million dollar business lines in online and food Chemical Engineer, University of Wisconsin PhD. technology venture-backed startups in Silicon Valley. Stanford Graduate School of Business MBA. Lee Chae, PhD Carol Lynn Berseth, MD Co-founder and CTO SVP Medical and Scientific Affairs Computational and molecular biologist leader Executive leader bridging technical and commercial with a track record of designing cutting-edge discovery teams for novel health product launches. Former methodologies for biomedicine, synthetic biology, Medical Director in Global Clinical Innovation at Mead agricultural biotech and food technology. Principal Johnson. 15+ years clinical experience and academic scientist in discoveries, including machine-learning research leadership at Mayo Clinic and Texas driven identification of functional food proteins and Children's Hospital. Drove portfolio of over 60 global computationally driven screens for novel metabolic clinical trials supporting over 200 global product genes and nutritional plant bioactives. UC Berkeley launches. PhD, Stanford Carnegie Institute of Plant Biology. 10 www.brightseedbio.com brightseed EFTA00284071 Top-tier advisory team Bernhard van Fred Levine, MD, PhD Valerio Nannini, MBA John SanGiovanni, PhD Lengerich, PhD Biochemical genetics and Former SVP Head of Chief of Unit on Genetics in inherited metabolic Strategies and Nutritional Neuroscience, diseases specialist. Performance of Nestle, National Institutes of Health, Former Chief Science Director of Sanford Health former head of Nestle Professor Georgetown Officer of General Mills Research Center Singapore School of Medicine SBP Sanford Burnham Prebys MEDICAL DISCOVERY INSTITUTE General Mills Peter Domaille, PhD Jed Fahey, ScD Jason Ryder, PhD Trent Northen, PhD Widely published Nutritional biochemist and 15 7 Expert in process and Director of High-Throughput researcher in analytical expert in plant physiology, product development in Biochemistry at the DOE quantitation and structure human nutrition and industrial biotech and food Joint Bioenergy Institute L, elucidation biochemistry, Director of tech. Advisory positions at and metabolomics leader at the Chemoprotection Bolt Threads, Amyris, the DOE's Joint Genome Center at Hopkins Miraculex Institute University Lawrencee nV Bolt SYNTHETIC GENOMICS National 0 MERCK tJPON) JOHNS HOPKINS AMYRIS. Threads Laboratory SCHOOL of MEDICINE 11 brightseed EFTA00284072 Supported by world-class investors Y CGC Horizons entures 50 fit ;*#',11:1 GERMIN8 AWUNDER 12 •: brightseed EFTA00284073