From: "Jeffrey E." <jeevacation@gmail.com>
To: Leon Black
Subject: it seems you need 2 numbers cac and alc - careful
Date: Thu, 12 Jan 2017 11:52:34 +0000
Type 2 diabetes mellitus (DM) is a well-established risk factor for the development of coronary heart disease
(CHD). Diabetic patients also have a higher mortality from CHD than patients without diabetesi '1 Patients with
type 2 DM are known to have elevated triglycerides and total cholesterol levels, in addition to reduced levels of
high-density lipoprotein.l2• 3] Not surprisingly, atherosclerosis is responsible for 80% of deaths in patients with
diabetes.01 Coronary artery calcium (CAC) has been shown to correlate histologically with the amount of
atheromatous plaque, which has a strong association with CHD.P, 63 Measurement of coronary calcium scores
by electron beam tomography (EBT) has been validated by numerous studies, and EBT is the most sensitive,
noninvasive method of detecting CHD.[6, 7] Patients with diabetes have been shown to have higher CAC scores,
reflecting increased atherosclerotic burden, and hence, increased cardiovascular risk in these patients. A recent
study by Qu et al[8] demonstrated that diabetic subjects with higher CAC scores had a 4-fold increased risk of
cardiac events. In addition, large studies have shown an increased risk of cardiac events in asymptomatic patients
with higher CAC sc
please note
The information contained in this communication is
confidential, may be attorney-client privileged, may
constitute inside information, and is intended only for
the use of the addressee. It is the property of
JEE
Unauthorized use, disclosure or copying of this
communication or any part thereof is strictly prohibited
and may be unlawful. If you have received this
communication in error, please notify us immediately by
return e-mail or by e-mail to jeevacation®gmail.com, and
destroy this communication and all copies thereof,
including all attachments. copyright -all rights reserved
EFTA01057107