To: Jeffrey Epsteinfleevacation©gmail.comj
From: jeffreyepsteinorg©gmail.com on behalf of
Sent Wed 7/17/2013 3:51:36 AM
Subject: Fwd: amyloid increases homocysteic acid toxicity
Forwarded message
From: Tohru
Date: The, Jul 16, 2013 at 7:00 PM
Suliect: am loid increases homoc stele acid toxici
To
Dear Christina;
I am afraid Jeffrey has a question about the relationship between amyloid beta and
homocysteic acid in blood for Alzheimer's disease process.
Amyloid hypothesis is still valid for preventing AD. We already observed that homocysteic
acid toxicity, especially, neurodegenerative toxicity, will increase in the presence of
amyloid.
However it has been observed that amyloid protein is present in normal brain, which
shows that amyloid itself has no toxicity for brain work.
Homocysteic acid has the original pathogen for AD process. Early onset of AD, familial AD,
has higher production of amyloid, which increases the homocysteic acid toxicity, then very
lower level of homocysteic acid can start the disease process. Recent reports indicate that
ApoE4 increases the permeability of blood brain barrier, which allows the invasion of
lower level of homocysteic acid in blood into brain.
This my hypothesis is strongly supported by my TSH1 recovery, because TSH1 decreased
homocysteic acid level in blood and blocked homocysteic acid toxicity in brain.
Now I am sincerely request your support.
EFTA_R1_00444219
EFTA01966177
Sincerely yours
Tohru
EFTA R1_00444220
EFTA01966178