EFTA00625051Set 9
40p15,170w
hours postdose. Both are subject to first-pass metabolism after oral dosing, resulting in
an absolute bioavailability of approximately 64% for norethindrone and 43% for ethinyl
estradiol.
The plasma norethindrone ... ethinyl estradiol pharmacokinetics following single- and
multiple-dose administrations of Loestrin 24 Fe tablets in 17 healthy female volunteers
are provided in Figures 1 and 2, and Table 1.
Following ... multiple-dose administration of Loestrin 24 Fe tablets, mean maximum
concentrations of norethindrone and ethinyl estradiol were increased by 95% and 27%,
respectively, as compared to single-dose administration. Mean
https://www.justice.gov/epstein/files/DataSet%209/EFTA00625051.pdf
EFTA00148081Set 9
2021-01-2741p24,032w
Reliance On Private Prisons.
OTHER WASHINGTON NEWS
• Biden Says US Ordering 200M More Vaccine Doses, Increasing Shipments To States.
• CDC Says Schools Can Resume In-Person Learning With Precautions.
• Administration ... selling fake COVID shots,
and in another case, the paramedic accused of stealing doses after making up fake patients,
now claiming his supervisor wanted the doses for his own family ... Matt Gutman added,
"In Florida, paramedic Joshua Colon accused of hoarding doses, claiming a supervisor wanted
them for his family. A tough-talking sheriff making an example of the pair
https://www.justice.gov/epstein/files/DataSet%209/EFTA00148081.pdf
EFTA00305920Set 9
13p8,636w
Balance to close (not including Buyer's dosing costs, prepaid items and prorations). AI funds pad
at dosing must be paid by locally drawn cad-rer's check, official bank ... Seller wit be entitled to retain the deposits if the transaction does not dose by the Closing Date unless
(1) the Property
43 appraises below the Puithase price and either ... Closing Date) at the time estate:shed by the dosing agent, by with tine Seller
so we (a) have removed al personal items and trash from the Property and swept
https://www.justice.gov/epstein/files/DataSet%209/EFTA00305920.pdf
EFTA01092032Set 9
25p12,760w
product composition, and delivery.
anon Kolbert Both types are manipulated. Athersys has safely delivered doses
of more than 1 billion cells systemically with no reported
immune reactions. Mesoblast has tested ... between an
allogeneic and autologous arm. The patients were further assigned to three increasing dose levels of 20,
100, and 200M cells. The primary endpoint of the study ... that they may
even be complimentary. MultiStem is given systemically in a large dose (possibly >billion cells) prior to 48
hours post injury to modulate inflammation, while the Cytomedix therapy
https://www.justice.gov/epstein/files/DataSet%209/EFTA01092032.pdf
EFTA00135832Set 9
2020-12-0835p21,405w
12/7, Rodriguez,
10.31M) reports the Administration "hopes to have close to 40 million doses of COVID-19 vaccine"
by the end of the year and "plans to distribute half ... hold back the other
EFTA00135850
half to give the same people their second dose of the two-shot regimen," but former FDA
commissioner and Pfizer board member Scott Gottlieb "says ... that's a bad idea. Instead, Gottlieb
says he would give out 35 million doses now, and presume the second doses will be available when
people need them
https://www.justice.gov/epstein/files/DataSet%209/EFTA00135832.pdf
EFTA01465999Set 10
2013-12-2319p4,004w
INDs filed during marketing suspension; 3)
potential for safer administration of Iclusig with lower doses in the
future; 4)
potential attempt at the frontline setting at lower doses as long ... spoke with at ASH are keeping patients on Iclusig
but on lower maintenance doses, and
are actively managing and monitoring patients. For patients who failed
Gleevec and second-generation products ... managing high blood pressure, high lipids, and other cardiovascular
symptoms; and using the lowest doses possible.
• Lower maintenance doses might improve safety. At ASH 2013, Cortez et al.
(abstract
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01465999.pdf
EFTA01734942Set 10
2016-09-1615p5,915w
with any drug development program, early clinical development should include appropriate
85 dose-finding in the target population to ensure that the most appropriate dosing regimen(s) are
86 selected ... further study. The FDA recommends evaluating more than one dose in phase 3
87 trials. See the following for additional information regarding dose response:
88
89 • The Fit-for-Purpose ... Initiative dose-finding tool MCP-MOD (Multiple Comparison
90 Procedure-modeling), a statistical methodology for dose response7
91
92 • The guidance for industry Exposure-Response Relationships — Study Design, Data
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01734942.pdf
EFTA00135950Set 9
2021-05-0740p24,825w
Pfizer And Moderna Vaccines Protect Against Variants.
• Pfizer Can Manufacture Up To 3B Vaccine Doses This Year.
• Foreign Health Officials Pause Distribution Of 38J Vaccines Made By Emergent.
• Pritzker Targets ... Petrosh's mother."
The Washington Post (5/6, 10.52M) describes the two women as "dose friends," saying the
"The grandmother did not keep that news to herself. She told ... Carter Evans added that "45% of eligible Americans have received at least one dose of
the vaccine." ABC World News Tonight (5/6, story 2, 3:30, Muir, 6.52M) reported
https://www.justice.gov/epstein/files/DataSet%209/EFTA00135950.pdf
EFTA00138991Set 9
2019-08-10148p32,818w
line Placed by Paramedics
Medications Epinephrine 1mg IV 08/10/2019 07:10
Epinephrine 3 doses and Sodium bicarb 2 doses administered by paramedics
CPR Compressions 08/10/2019 07:11
Medications Sodium Bicarbonate ... Location: Back-Middle
Quality of Pain: Shooting
Pain Scale: 5
Intervention: MEDROL DOSE PACK
Trauma Date/Year:
Injury:
Mechanism:
Onset: 5+ Years
Duration: 5+ Years
Exacerbating Factors: NO EXERCISE
Relieving Factors ... MEDROL DOSE PACK
Reason Not Done:
Comments:
Seen for clinic(s): Orthopedic/Rheumatology, Pulmonary/Respiratory, Endocrine/Lipid
Added to clinic(s): Orthopedic/Rheumatology, Pulmonary/Respiratory, Endocrine/Lipid
OBJECTIVE:
Exam:
General
Appearance
Yes: Appears Well, Alert
https://www.justice.gov/epstein/files/DataSet%209/EFTA00138991.pdf
EFTA00673207Set 9
2015-10-2534p11,593w
around one in five U.S. adults did
not fill out their prescription or skipped doses because of the costs of medicines in 2013. The
proportion was less than ... read these emails, and just look what happened to him!" It doesn't come dose to
passing the laugh test. And I assume Republicans know it.
But for me, Trey ... little better for
them than the inactivated injected vaccine. Children were given two doses to inhale initially so,
theoretically, they could quickly build immunity. But it turned out the nasal
https://www.justice.gov/epstein/files/DataSet%209/EFTA00673207.pdf
EFTA00121315Set 9
2019-07-2381p16,805w
Location: Back-Middle
Quality of Pain: Shooting
Pain Scale: 5
Intervention: MEDROL DOSE PACK
Trauma Date/Year:
Injury:
Mechanism:
Onset: 5+ Years
Duration: 5+ Years
Exacerbating Factors: NO EXERCISE
Relieving Factors ... MEDROL DOSE PACK
Reason Not Done:
Comments:
Seen for clinic(s): Orthopedic/Rheumatology, Pulmonary/Respiratory, Endocrine/Lipid
Added to clinic(s): Orthopedic/Rheumatology, Pulmonary/Respiratory, Endocrine/Lipid
OBJECTIVE:
Exam:
General
Appearance
Yes: Appears Well, Alert ... Location: Back-Middle
Quality of Pain: Shooting
Pain Scale: 5
Intervention: MEDROL DOSE PACK
Trauma Date/Year:
Injury:
Mechanism:
Onset: 5+ Years
Duration: 5+ Years
Exacerbating Factors: NO EXERCISE
Relieving Factors
https://www.justice.gov/epstein/files/DataSet%209/EFTA00121315.pdf
EFTA00598642Set 9
230p95,432w
environment.
EFTA00598660
24 NUTRITION& CARE
IT'S ALL IN
THE MIX
Adding correctly dosed amino acids from Evonik to amino acids are optimally metabolized only if they are
animal feed ... around livestock and animal feed. Animal feed accounts plete systems for their targeted dosing. To accomplish
for between 60 and 70 percent of the total cost of meat this ... special analyses, consultation, and
challenge by adjusting the nutrients in their animal feed to dosing systems. For example, on behalf of its customers
precisely meet the needs of particular animal
https://www.justice.gov/epstein/files/DataSet%209/EFTA00598642.pdf