EFTA01850362Set 10
2011-11-087p3,025w
destruction within the margin of the lesion due to a more
pronounced shutdown of microvascular perfusion, resulting in irreversible ischemia (21,221. In addition. as ins well known that
thawing ... fact that the double freeze procedure provides a more distinct microvascular shutdown at the
margin of the cryolesion compared to the single freeze procedurel21,251. which can prevent rapid marginal ... attributed to the abrogation of the "heat sink effect" due to
the lack of microvascular perfusion[1,8).
Antifreeze proteins
EFTA_R1_00243261
EFTA01850365
It have been shown that antifreeze
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01850362.pdf
EFTA01741615Set 10
2011-11-087p3,030w
destruction within the margin of the lesion due to a more
pronounced shutdown of microvascular perfusion, resulting in irreversible ischemia (21,221. In addition. as ins well known that
thawing ... fact that the double freeze procedure provides a more distinct microvascular shutdown at the
margin of the cryolesion compared to the single freeze procedurel21,251. which can prevent rapid marginal ... attributed to the abrogation of the "heat sink effect" due to
the lack of microvascular perfusion[1,8).
Antifreeze proteins
EFTA_R1_00031723
EFTA01741618
It have been shown that antifreeze
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01741615.pdf
EFTA02031879Set 10
2011-11-087p3,029w
destruction within the margin of the lesion due to a more
pronounced shutdown of microvascular perfusion, resulting in irreversible ischemia (21,221. In addition. as ins well known that
thawing ... fact that the double freeze procedure provides a more distinct microvascular shutdown at the
margin of the cryolesion compared to the single freeze procedurel21,251. which can prevent rapid marginal ... attributed to the abrogation of the "heat sink effect" due to
the lack of microvascular perfusion[1,8).
Antifreeze proteins
EFTA_R1_00542170
EFTA02031882
It have been shown that antifreeze
https://www.justice.gov/epstein/files/DataSet%2010/EFTA02031879.pdf
EFTA00596383Set 9
14p4,018w
EFTA00596393
blood test results (e.g., from 8.0% to 7.0%) can reduce the risk of microvascular complications
(eye, kidney, and nerve diseases) by 40%.
• In patients with type 1 diabetes, intensive ... stroke)
among persons with diabetes by 33% to 50%, and the risk of microvascular complications
(eye, kidney, and nerve diseases) by approximately 33%.
• In general, for every
https://www.justice.gov/epstein/files/DataSet%209/EFTA00596383.pdf