EFTA00315100Set 9
14p13,437w
protocol, the authors performed retrospective 50-hour WGS to confirm, in two children, known molecular
diagnoses that had been made using other methods. Next, prospective WGS revealed a molecular diagnosis ... many feature clinical and genetic heterogeneity. Hence, an immense unmet need
exists for improved molecular diagnosis in infants. Because disease progression is extremely rapid, albeit hetero-
geneous, in newborns, molecular ... neonatal intensive care units. Ret-
rospective 50-hour WGS identified known molecular diagnoses in two children. Prospective WGS disclosed potential
molecular diagnosis of a severe G22-related skin disease
https://www.justice.gov/epstein/files/DataSet%209/EFTA00315100.pdf
EFTA00606068Set 9
2017-05-0812p8,894w
Here we use binding site predictions on tubulin, the protein subunit of
microtubules, with molecular docking simulations, quantum chemistry calculations, and theoretical
modeling of collective dipole interactions in tubulin ... relationship of general anesthetics, as
effective agents can span a 35-fold range in molecular volume from a single atom (xenon) to 56-atom steroids,
with numerous types of chemical ... PORTS17: 9877 IDOI:10.1038N41598-017-09992-7 3
EFTA00606070
for lipid solubility and molecular polarizability for these non-anesthetic agents compared to anesthetics (Fig. 2C,
Table Si). Thus
https://www.justice.gov/epstein/files/DataSet%209/EFTA00606068.pdf
EFTA02683561Set 11
2014-09-249p2,522w
depression conducted at the University by Professor Paul Greengard, head of the
Laboratory of Molecular and Cellular Neuroscience, and Professor Nathaniel Heintz,
head of the Laboratory of Molecular Biology. These ... funds are specifically directed
toward a new research initiative to apply the most modern molecular and genetic
approaches available to development of new therapeutic strategies for the treatment ... EFTA02683565
ATTACHMENT A
Toward Development of New Treatments for Obsessive-Compulsive and
Comorbid Disorders
Molecular dissection of the cortico-striatal-thalamo-cortical (CSTC) circuits
controlling obsessive compulsive, depressive, and anxious
https://www.justice.gov/epstein/files/DataSet%2011/EFTA02683561.pdf
EFTA01127977Set 9
2014-09-249p2,510w
depression conducted at the University by Professor Paul Greengard, head of the
Laboratory of Molecular and Cellular Neuroscience, and Professor Nathaniel Heintz,
head of the Laboratory of Molecular Biology. These ... funds are specifically directed
toward a new research initiative to apply the most modern molecular and genetic
approaches available to development of new therapeutic strategies for the treatment ... EFTA01127981
ATTACHMENT A
Toward Development of New Treatments for Obsessive-Compulsive and
Comorbid Disorders
Molecular dissection of the cortico-striatal-thalamo-cortical (CSTC) circuits
controlling obsessive compulsive, depressive, and anxious
https://www.justice.gov/epstein/files/DataSet%209/EFTA01127977.pdf
EFTA00586852Set 9
90p36,976w
inefficiencies in the diagnosis, treatment and delivery of health care at the convergence of
molecular medicine, electronic sensor technology and communication platforms. On the other end
of the spectrum ... sequenced at 30x coverage in a day for SI,000.
The rise of molecular medicine is a classic technology-based transformation similar to the advent of
the digital information ... diseases are characterized based on cell
biology rather than symptoms or point of origin. Molecular profiling based on this taxonomy will
allow for highly accurate and differentiated diagnostics. The sequencing
https://www.justice.gov/epstein/files/DataSet%209/EFTA00586852.pdf
EFTA00841445Set 9
2015-11-057p2,225w
clinical tests reported in the third quarter, 25% year-over-year
growth;
* Broadening molecular information solutions with the launch of GeneKitTM, a
genomic solutions portal for pathologists, and expanding FoundationCOREA ... diverse revenue
streams generated by biopharmaceutical customers engaged with the company in clinical trial, molecular information
data access, and companion diagnostic development activities.
"Foundation Medicine delivered 54% year-over-year ... October, Roche Pharmaceuticals (Israel) Ltd. commenced
commercial activities in support of the company's molecular information
products in oncology. Roche Israel will act as the exclusive distributor
of Foundation Medicine
https://www.justice.gov/epstein/files/DataSet%209/EFTA00841445.pdf
EFTA01196229Set 9
13p4,675w
companies at the intersection of medicine, life sciences and
digital technology. Recent advances in molecular medicine, electronic sensor technology, and
communication platforms create a significant opportunity to dramatically increase efficiencies ... well as becoming increasingly personalized.
Investment Focus:
Biosys is focused on three areas:
I. Molecular Medicine. Biosys will invest in opportunities that make possible the identification,
development and delivery ... more effective and efficient treatments through molecular
medicine, genomics and bio-informatics. Medicine is evolving toward a regime of
personalization through a positive feedback loop involving the consumer, treatment
https://www.justice.gov/epstein/files/DataSet%209/EFTA01196229.pdf
EFTA00605561Set 9
10p9,789w
taken for granted: it tacitly separates the assumption has changed society. the atomic and molecular structure of
imaginable from the unimaginable. If an We have discarded many other as- matter ... rocket throat nozzles, now, it is a relatively minor problem.
chemical bond, and the molecular basis and silicon single crystals. Most of us now alive will die of cardio ... Inheritance certainly
and chemistry offers much to the effort. engineering a molecular interface be- makes a difference.
This Essay is about the assumptions tween them, but designing this interface Molecular
https://www.justice.gov/epstein/files/DataSet%209/EFTA00605561.pdf
EFTA00633452Set 9
2014-01-073p872w
Jeffrey Epstein acevacation@gmail.comr
Subject: FW: Foundation Medicine Extends and Expands Collaboration to Provide Molecular Information
and Genomic Profiling for Clinical Oncology Programs
Date ... Boris Nikolic
Subject: Foundation Medicine Extends and Expands Collaboration to Provide Molecular Information and Genomic
Profiling for Clinical Oncology Programs
;t,Logo
Jan. 6, 2014 21:30 UTC
Foundation Medicine ... Extends and Expands Collaboration to Provide Molecular
Information and Genomic Profiling for Clinical Oncology Programs
CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Foundation Medicine today announced it has extended
and expanded its ongoing
https://www.justice.gov/epstein/files/DataSet%209/EFTA00633452.pdf
EFTA02444545Set 11
10p9,814w
taken for granted: it tacitly separates the assumption has changed society. the atomic and molecular structure of
imaginable from the unimaginable. If an We have discarded many other as- matter ... rocket throat nozzles, now, it is a relatively minor problem.
chemical bond, and the molecular basis and silicon single crystals. Most of us now alive will die of cardio ... Inheritance certainly
and chemistry offers much to the effort. engineering a molecular interface be- makes a difference.
This Essay is about the assumptions tween them, but designing this interface Molecular
https://www.justice.gov/epstein/files/DataSet%2011/EFTA02444545.pdf
EFTA00586577Set 9
2014-01-2825p1,978w
several areas:
• Drug Discovery
• Research Tools
• Diagnostics
• mAB-Similar Products
• Autoimmune/Allergy Therapy
• Viral Therapeutics
• Molecular Sensors
OH2 is a holding company, ultimately intending to form subsidiaries to monetize each ... Laboratories, LLC
Confidential and Proprietary
EFTA00586584
mAB-Similar Products
mAbQT't' offers new molecular therapeutics:
— Target-designed to be similar to monoclonal antibodies, but
easier to produce.
— Engineered to reduce ... Lassa - for rapid reduction of viral loads.
OH2 Laboratories, LLC
Confidential and Proprietary
EFTA00586587
Molecular Sensors
Due to their stability, low-cost and high degree of molecular
selectivity, Receptorsc/TY
https://www.justice.gov/epstein/files/DataSet%209/EFTA00586577.pdf
EFTA01620819Set 10
5p3,497w
with vascular plants. To
Fungal associations of basal test this possibility, we carried out molecular and microscopical
vascular plants: reopening a analyses of the fungal associations of all the major ... plant colony was collected from each
Introduction site. Plants were processed for cytological and molecular analyses
The widely held hypothesis that Glomeromycota fungi alone within 1 wk of collection ... lines of et al, 2010; Desire end, 2013). Extraction and sequencing of
evidence from molecular, cytological, functional and palaeonto- genomic fungal DNA were performed using the method of
logical studies
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01620819.pdf
EFTA00308046Set 9
2008-01-239p3,034w
Cambridge St, Suite 340, Room 382, Boston
Jonathan I. Matsui, PhD
Lecturer on Molecular & Cellular Biology, Harvard University
Neurobiology Concentration Advisor for Harvard College Undergraduates, Harvard Faculty of Arts & Sciences ... happens to linguistic and musical abilities if
congenital or acquired diseases alter their underlying molecular substrates and neural
circuitry?
In this 13-week lecture course, current knowledge and conceptual insights ... Auditory Neurobiology, 2) Auditory Communication•,
3) Signal Processing b. the Auditory Systenr, 4) Molecular Biology of the Auditory System, and 5)
Developmental Biology of the Auditoy System. We introduce data
https://www.justice.gov/epstein/files/DataSet%209/EFTA00308046.pdf
EFTA02444651Set 11
2008-11-0638p10,506w
microchannels, the liquids 11.
flowing through the channel will not mix except by
molecular diffusion; thus, the flow is laminar and the two
liquids flowing side-by-side form ... wettability of surfaces on the 0.1- to 1-
micrometer scale through micromachining and molecular
self-assembly." Science (1992), 257(5075), 1380-2.
S
3. Kumar, A., Biebuyck ... native protein. We are currently Man .
using modeling and simulations to investigate the molecular
details behind the reduced stability of the charged
derivatives relative to the native protein. Figure
https://www.justice.gov/epstein/files/DataSet%2011/EFTA02444651.pdf