SNAP25
generally associated with an increase of neuronal excitability.
However, disruption of Nhel results in a more complex phenotype
with increased Na'-current density in hippocampal neurons Fig. 1. Presynaplic ... agreement with the classification of NDCBE as an
this study suggest that Nhel activity may not only affect presynap- acid extruder, Slc4a8 deficient neurons displayed a lower steady
tic vesicle ... Nature 345, 347-350. G.E. and Scott, W.J.(1999)Targeted disruption of the murine Nhel
143] Tang, C.M., Dichter. M. and Morad. M. (1990) Modulation of the N-methyl