EFTA01195776Set 9
2014-01-088p6,422w
Science Altered Placebo and Drug Labeling Changes the Outcome of Episodic
Translational
Medicine Migraine Attacks
AAAS
Slavenka Kam-Hansen et al.
Sci Transl Med 6, 218ra5 (2014);
DOI: 10.1126/scitranslmed.3006175 ... Editor's Summary
Placebo and Medication Effects in Episodic Migraine
Placebo and medication effects are intimately related in clinical practice and drug development. In new work,
Kam-Hansen ... negative" to "neutral" to "positive"—provided to
patients, who received either active drug or placebo, modified their headache pain as measured by patient-reported
pain scores. In a randomized order
https://www.justice.gov/epstein/files/DataSet%209/EFTA01195776.pdf
EFTA00603108Set 9
2010-08-247p6,174w
OPEN a ACCESS Freely available online PI oS one
Clinical Trial
Placebos without Deception: A Randomized Controlled
Trial in Irritable Bowel Syndrome
Ted J. Kaptchuk''2•, Elizabeth Friedlander', John ... Psychology, UnNersity of Hull, Hull, United Kingdom
able physiological changes in response to placebo treatment that
Abstract could explain how placebos alter symptoms. [2] A critical question
is establishing ... physicians mid other providers can take
Background: Placebo treatment can significantly influ- optimal advantage of placebo effects consistent with their
ence subjective symptoms. However, it is widely believed responsibility
https://www.justice.gov/epstein/files/DataSet%209/EFTA00603108.pdf
EFTA01155955Set 9
2010-08-247p6,174w
OPEN a ACCESS Freely available online PI oS one
Clinical Trial
Placebos without Deception: A Randomized Controlled
Trial in Irritable Bowel Syndrome
Ted J. Kaptchuk''2•, Elizabeth Friedlander', John ... Psychology, UnNersity of Hull, Hull, United Kingdom
able physiological changes in response to placebo treatment that
Abstract could explain how placebos alter symptoms. [2] A critical question
is establishing ... physicians mid other providers can take
Background: Placebo treatment can significantly influ- optimal advantage of placebo effects consistent with their
ence subjective symptoms. However, it is widely believed responsibility
https://www.justice.gov/epstein/files/DataSet%209/EFTA01155955.pdf
EFTA02695679Set 11
7p6,626w
SCIENCE mystified, thirty-five years later. "It had to
be some kind of placebo, but I had never
given the idea of a placebo effect much a
THE POWER ... alone allowed words like "ritual" and
"belief" to seep into a conversation about
medicine. Placebos had a bad name,
which is not surprising, since they have
been used primarily ... definition of medical treatment is chang
ing, and so arc attitudes about placebos.
This year, Harvard created an institute
dedicated wholly to their study, the Pro-
gram in Placebo Studies
https://www.justice.gov/epstein/files/DataSet%2011/EFTA02695679.pdf
EFTA00625099Set 9
30p10,397w
DOSAGE AND ADMINISTRATION).
Pharmacodynamics
Effects of VIAGRA on Erectile Response: In eight double-blind, placebo-controlled crossover
studies of patients with either organic or psychogenic erectile dysfunction, sexual stimulation
resulted ... objective measurement of hardness and
duration of erections (RigiScan®), after VIAGRA administration compared with placebo. Most
studies assessed the efficacy of VIAGRA approximately 60 minutes post dose. The erectile
response ... most notable approximately 1-2 hours after dosing, and was not different than placebo at 8 hours.
Similar effects on blood pressure were noted with
https://www.justice.gov/epstein/files/DataSet%209/EFTA00625099.pdf
EFTA02435994Set 11
24p7,578w
homosexuality—the effects of denial and disclosure
Positive affect and immune function
The placebo—immune effects
1
EFTA_R1_01508284
EFTA02435994
The immunology of self-deception is an important subject ... either direction. Repression and disclosure, optimism, meditation, positive
emotions and negative, religiosity and the placebo effect—all have important
immune correlates. The underlying question is always why. Why should
suppression ... closest competitor,
degree of bodily symmetry, explains only 6% of variance in survival.
The placebo: immune effects?
The placebo effect refers to the fact that a chemically inert or innocuous
https://www.justice.gov/epstein/files/DataSet%2011/EFTA02435994.pdf
EFTA00630141Set 9
2016-08-013p772w
From: Deepak Chopra
To: jeffrey E. <jeevacation@gmail.com>
Subject: Re: Fw: Exploring the placebo effect
Date: Mon, 01 Aug 2016 00:39:58 +0000
yes sir I
The Chopra Foundation ... Deepak Chopra
Subject: Re: Fw: Exploring the placebo effect
how much fun.
On Sun, Jul 31, 2016 at 8:23 PM, Deepak Chopra > wrote:
Thanks to you !
The Chopra Foundation ... Deepak Chopra
Cc: Eric Schadt; Rudolph Tanzi; Carolyn Rangel
Subject: Re: Exploring the placebo effect
This is indeed very interesting! I am currently in Cuba. But will reach
https://www.justice.gov/epstein/files/DataSet%209/EFTA00630141.pdf
EFTA00650387Set 9
2016-07-312p497w
From: Deepak Chopra
To: Jeff Epstein
Subject: Fw: Exploring the placebo effect
Date: Sun, 31 Jul 2016 23:49:32 +0000
After our discussion on placebo -I explored what ... July 31, 2016 7:37 PM
To: Deepak Chopra; Rudolph Tanzi
Subject: Exploring the placebo effect
Deepak and Rudy,
Given the identification of a strong "vacation" and "meditation" molecular response ... study, I became
interested in whether such a molecular response could exist in the placebo arms of clinical trials. As you know, in the
placebo arms of clinical trials there
https://www.justice.gov/epstein/files/DataSet%209/EFTA00650387.pdf
EFTA00823011Set 9
2016-08-012p641w
From: Deepak Chopra
To: Jeff Epstein <jeevacation(ciginail.corn>
Subject: Fw: Exploring the placebo effect
Date: Mon, 01 Aug 2016 00:23:56 +0000
Thanks to you !
2013 Costa ... Deepak Chopra
Cc: Eric Schadt; Rudolph Tanzi; Carolyn Rangel
Subject: Re: Exploring the placebo effect
This is indeed very interesting! I am currently in Cuba. But will reach ... July 31, 2016 7:37 PM
To: Deepak Chopra; Rudolph Tanzi
Subject: Exploring the placebo effect
Deepak and Rudy,
Given the identification of a strong "vacation" and "meditation" molecular response
https://www.justice.gov/epstein/files/DataSet%209/EFTA00823011.pdf
EFTA00823013Set 9
2016-08-013p746w
From: "Jeffrey E." <jeevacation@gmail.com>
To: Deepak Chopra
Subject: Re: Fw: Exploring the placebo effect
Date: Mon, 01 Aug 2016 00:39:15 +0000
how much ... Deepak Chopra
Cc: Eric Schadt; Rudolph Tanzi; Carolyn Rangel
Subject: Re: Exploring the placebo effect
This is indeed very interesting! I am currently in Cuba. But will reach ... July 31, 2016 7:37 PM
To: Deepak Chopra; Rudolph Tanzi
Subject: Exploring the placebo effect
Deepak and Rudy,
Given the identification of a strong "vacation" and "meditation" molecular response
https://www.justice.gov/epstein/files/DataSet%209/EFTA00823013.pdf
EFTA00823009Set 9
2016-08-012p654w
From: Deepak Chopra <
To: Jeff Epstein <jeevacation(ciginail.com>
Subject: Fw: Exploring the placebo effect
Date: Mon, 01 Aug 2016 00:19:26 +0000
See what you started !!!! The head ... Deepak Chopra
Cc: Eric Schadt; Rudolph Tanzi; Carolyn Rangel
Subject: Re: Exploring the placebo effect
This is indeed very interesting! I am currently in Cuba. But will reach ... July 31, 2016 7:37 PM
To: Deepak Chopra; Rudolph Tanzi
Subject: Exploring the placebo effect
Deepak and Rudy,
Given the identification of a strong "vacation" and "meditation" molecular response
https://www.justice.gov/epstein/files/DataSet%209/EFTA00823009.pdf
EFTA00823017Set 9
2016-08-013p766w
From: "Jeffrey E." <jeevacation@gmail.com>
To: Deepak Chopra
Subject: Re: Fw: Exploring the placebo effect
Date: Mon, 01 Aug 2016 00:40:02 +0000
there is a very famous book called ... Deepak Chopra
Cc: Eric Schadt; Rudolph Tanzi; Carolyn Rangel
Subject: Re: Exploring the placebo effect
This is indeed very interesting! I am currently in Cuba. But will reach ... July 31, 2016 7:37 PM
To: Deepak Chopra; Rudolph Tanzi
Subject: Exploring the placebo effect
Deepak and Rudy,
Given the identification of a strong "vacation" and "meditation" molecular response
https://www.justice.gov/epstein/files/DataSet%209/EFTA00823017.pdf
EFTA00877791Set 9
2011-11-215p1,055w
Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email:
Web: www.programinplacebostudies.org ... Kaptchuk
Associate Professor of Medicine
Harvard Medical School
EFTA00877791
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email:
Web: www.programinplacebostudies.org ... Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email
https://www.justice.gov/epstein/files/DataSet%209/EFTA00877791.pdf
EFTA01772729Set 10
2011-11-175p894w
Kaptchuk
Associate Professor of Medicine
Harvard Medical 5=hool
Director, Program in Placebo Srudies & Therapeutic Encounter Beth l=rael Deaconess Medical Center Boston,
MA=02215
Email:
Web: www.programinplacebostudies.org ... essor of Medicine
EFTA_R1_00085088
EFTA01772729
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Enco=nter
Beth Israel Deaconess Medical Center
Boston. MA 02215
Email:
Web: www.programinp ... wrote:
Dear Jeffrey,
<=div>
I wanted to update you on our placebo initiative at Harvard. &nbs=;I've been asked to start a
Harvard-wide Program in Placebo Studies which
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01772729.pdf
EFTA00687387Set 9
2011-11-174p936w
Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email ... Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email:
Web:
EFTA00687387 ... wrote:
Dear Jeffrey,
I wanted to update you on our placebo initiative at Harvard. I've been asked to start a Harvard-wide
Program in Placebo Studies which will
https://www.justice.gov/epstein/files/DataSet%209/EFTA00687387.pdf
EFTA01853039Set 10
2011-11-176p930w
Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Web: www.programinplacebostudies.orq ... Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Web: www.orograminplacebostudies.orq
EFTA_R1_00248369
EFTA01853039 ... wrote:
Dear Jeffrey,
I wanted to update you on our placebo initiative at
Harvard. I've been asked to start a Harvard-wide
Program in Placebo Studies which will
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01853039.pdf
EFTA01985474Set 10
2011-11-176p946w
Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Email
Web: www.programinplacebostudies.org ... Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston MA 02215
Email:
Web: www programinplacebostudies.org
EFTA ... terote:
Dear Jeffrey,
I wanted to update you on our placebo initiative at
Harvard. I've been asked to start a Harvard-wide
Program in Placebo Studies which will
https://www.justice.gov/epstein/files/DataSet%2010/EFTA01985474.pdf
EFTA00877783Set 9
2011-11-215p996w
Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email:
Web: www.programinplacebostudies.org ... EFTA00877783
Ted J. Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email:
Web: www.programinplacebostudies.org ... wrote:
Dear Jeffrey,
I wanted to update you on our placebo initiative at Harvard. I've been asked to start a Harvard-wide
Program in Placebo Studies which will
https://www.justice.gov/epstein/files/DataSet%209/EFTA00877783.pdf
EFTA00877775Set 9
2011-11-214p973w
Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
Boston, MA 02215
Phone:
Email:
Web: www.programinplacebostudies.org ... Kaptchuk
Associate Professor of Medicine
Harvard Medical School
Director, Program in Placebo Studies & Therapeutic Encounter
Beth Israel Deaconess Medical Center
EFTA00877775
Boston, MA 02215
Phone:
Email:
Web: www.programinplacebostudies.org ... wrote:
Dear Jeffrey,
I wanted to update you on our placebo initiative at Harvard. I've been asked to start a Harvard-wide
Program in Placebo Studies which will
https://www.justice.gov/epstein/files/DataSet%209/EFTA00877775.pdf