Epstein Files Search

EFTA01045495Set 9

2018-05-2936p8,101w

Alzheimer's disease (AD). These neurovascular enhancements were associated with reduced mechanistic target of rapamycin (mTOR) and increased endothelial nitric oxide synthase (eNOS) protein expressions. KD also increased the relative ... previously reported that inhibiting mechanistic target of rapamycin (mTOR) signaling increases neurovascular function by activating endothelial nitric oxide synthase (eNOS)nn. In this study, we also found that mTOR protein ... from one preparation of 10 mice per group, "'Pp< 0.001. mTOR: mechanistic target of Rapamycin; P-gp: P-glycoprotein; eNOS; endothelial nitric oxide synthase. Full size image Ketogenic diet alters

https://www.justice.gov/epstein/files/DataSet%209/EFTA01045495.pdf

EFTA00620069Set 9

26p10,915w

effect on longevity, it's a drug that inhibits the mammalian target of rapamycin (mTOR). I'll explain why. A brief word on caloric restriction and mTOR inhibition Caloric restriction ... bone density, making us more vulnerable to injury and trauma. Mammalian target of rapamycin (mTOR) Mammalian target of rapamycin (mTOR) is a protein—found inside of cells—critical for cell ... longevity, it may be that both approaches—directly inhibiting mTOR with a drug like rapamycin and indirectly inhibiting mTOR via dietary strategies that reduce insulin/IGF/GH as upstream signals-affect similar

https://www.justice.gov/epstein/files/DataSet%209/EFTA00620069.pdf

EFTA02253135Set 11

2018-08-131p198w

8/13/2018 11:00:13 AM Subject: Podcast is live: David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity? (EP.09) Title: Podcast is live ... David Sabatini, M.D, Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity? (EP.09) Greetings - Released a new episode this morning: David Sabatini, NI. D., Ph.D,: raaanwei

https://www.justice.gov/epstein/files/DataSet%2011/EFTA02253135.pdf

EFTA01735494Set 10

2010-11-0418p3,836w

Linkage Between the Phosphoinositide 3-Kinase-AKT Signaling Pathway and the Mammalian Target of Rapamycin in Mitogen-Stimulated and Transformed Cells Lower Bound for Sparse Euclidean Spanners. 5. Radhika Nagpal

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01735494.pdf

EFTA02077324Set 10

2015-05-263p368w

poop' (easiest way I can think of to describe it). Apparently, rapamycin (sirolimus) has been shown to slow aging and solve neuro-degenerative disorders in mice and fruit flies

https://www.justice.gov/epstein/files/DataSet%2010/EFTA02077324.pdf

EFTA00480157Set 9

2018-08-122p512w

anyone that knows me, there's not much more I like thinking about than rapamycin, mTOR, and longevity. I was a kid in a candy store when we recorded this

https://www.justice.gov/epstein/files/DataSet%209/EFTA00480157.pdf

EFTA00726413Set 9

2010-11-0418p3,834w

Linkage Between the Phosphoinositide 3-Kinase-AKT Signaling Pathway and the Mammalian Target of Rapamycin in Mitogen-Stimulated and Transformed Cells Lower Bound for Sparse Euclidean Spanners. 5. Radhika Nagpal

https://www.justice.gov/epstein/files/DataSet%209/EFTA00726413.pdf

EFTA01612589Set 10

1p42w

Attis +1 (212) 533-3739 • 2017/10/25 Peter Attis Great #. I tied to get 917-RAPAMYCin... but it was taken... 02:16:47 am ✓ Read

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01612589.pdf

EFTA02491798Set 11

2015-08-071p169w

with you in NM re: Easter Island. Are you familiar with the discovery of rapamycin? From: jeffrey E. [mailto:jeevacation@gmail.comj Sent: Thursday, August 06, 2015 4:23 PM To: Peter

https://www.justice.gov/epstein/files/DataSet%2011/EFTA02491798.pdf

EFTA02256465Set 11

2018-08-122p487w

anyone that knows me, there's not much more I like thinking about than rapamycin, mTOR, and longevity. I was a kid in a candy store when we recorded this

https://www.justice.gov/epstein/files/DataSet%2011/EFTA02256465.pdf

EFTA02417369Set 11

2010-11-0418p3,844w

Linkage Between the Phosphoinositide 3-Kinase-AKT Signaling Pathway and the Mammalian Target of Rapamycin in Mitogen-Stimulated and Transformed Cells Lower Bound for Sparse Euclidean Spanners. 5. Radhika Nagpal

https://www.justice.gov/epstein/files/DataSet%2011/EFTA02417369.pdf