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EFTA00742494Set 9

2010-07-136p4,914w

medical text Date: Tue, 13 Jul 2010 17:29:13 +0000 Treatment of carcinoid tumors and the carcinoid syndrome Authors Shanthi V Sitaraman MD PhD. FRCP Stephen E Goldfinger ... constellation of symptoms mediated by various humoral factors elaborated by some carcinoid tumors (table 1) [1]. Two of the most common manifestations are flushing and diarrhea (table 2). (See "Clinical ... features of the carcinoid syndrome".) Management of patients with these tumors should include: • Localization of the tumor and possible metastases by CT scan and somatostatin receptor scintigraphy Rat (See "Diagnosis

https://www.justice.gov/epstein/files/DataSet%209/EFTA00742494.pdf

EFTA00603737Set 9

Bozic. Let Accumulation of driver and passenger mutations during tumor 24. Talmadge.J. E. & I.J.AACR Centennial Series: the !hom of cancer progression. Proc. NatI Acad. Sci USA 107.18545-18550 (2010). metastasis ... Andersco.A. R. A. Weaver. A. M.. Cummings. P. T.& Quaranta. V. Tumor Pathot. 66.928-932 (2013). morphology and phenotypic evolution driven by selective pressure from the 30. Winter ... Modeting S.M.acknowledge support from The Virginia and M. Ludwig Fund for Cancer tumor-associated edema in gliomas during anti-angiogenic therapy and its Research. The Lustgarten Foundation for Pancreatic Cancer

https://www.justice.gov/epstein/files/DataSet%209/EFTA00603737.pdf

EFTA01168775Set 9

2015-09-2838p11,652w

growth curve and mouse xenograft model to investigate the effects of PGK1 on tumor formation and apoptosis EFTA01168778 2 Barrow Neurological Institute- Phoenix, AZ: Researcher 2011-2015 PI: Dr. Anna ... implement the program in all high schools within the district Students Supporting Brain Tumor Research-ASU: Event Chair and Mayo Clinic Officer 2012-2013 -Manage and execute events that raise ... awareness about brain tumors; invited the Principal Investigator of Neuro-Oncology at Barrow Neurological Institute to present research to students -Promoted a walk-a-thon held at Saguaro High School

https://www.justice.gov/epstein/files/DataSet%209/EFTA01168775.pdf

EFTA02031879Set 10

2011-11-087p3,029w

Figure 1-8-11). Figure 1-8-10. Average viability 6 standard deviation of tumor morse From Robrnson> D. et al. Cryob&ogy 2001.43.4-10 EFTA_R1_00542168 EFTA02031880 ... experiments with human prostatic adenocarcinoma grown subcutaneously in nude mice. Prior to cryosurgery, the tumors of test mice were injected interstitially with AFP-l. In control mice, the tumors were ... Figure 1-8-13. Typical micrographs of the j b. Obtained from prostate cancer tumors that were injected with phosphate-buffered saline solution prior to freezing; ?c. ?Obtained from tumors

https://www.justice.gov/epstein/files/DataSet%2010/EFTA02031879.pdf

EFTA00661247Set 9

2011-11-083p3,128w

cycles (Figure 1-8.11). Figure 1-8-10. Average viability 8 standard deviation of tumor morsels (expressed as optical density per 100 mg wet weir t) From Rolinson7 ... experiments with human prostate adenocardnoma grown subcutaneously in rude mice. Prior to cryosurgery. the tumors of test mix were injected interstitially win AFRI. In control mice, the tumors were injected ... tissue before (a) and after cryosurgery (b) and (e) b. Obtained from prostate cancer tumors that were injected with pheSphate.buffeled saline solution IMO( to freezing: ?O.? Obtained from tumors that

https://www.justice.gov/epstein/files/DataSet%209/EFTA00661247.pdf

EFTA01850362Set 10

2011-11-087p3,025w

Figure 1-8-11). Figure 1-8-10. Average viability 6 standard deviation of tumor morse From Robrnson> D. et al. Cryob&ogy 2001.43.4-10 EFTA_R1_00243259 EFTA01850363 ... experiments with human prostatic adenocarcinoma grown subcutaneously in nude mice. Prior to cryosurgery, the tumors of test mice were injected interstitially with AFP-l. In control mice, the tumors were ... Figure 1-8-13. Typical micrographs of the j b. Obtained from prostate cancer tumors that were injected with phosphate-buffered saline solution prior to freezing; ?c. ?Obtained from tumors

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01850362.pdf

EFTA01201684Set 9

2010-10-087p6,726w

tations in patients with metastatic cancers. disease burden, but in most cases, the tumor returns as a conse- First mathematical investigations of the evolution of resistance quence of resistance. Various ... including mutation of target bility that cells resistant to chemotherapy are present in a tumor genes and activation of other drivers. There is increasing evidence of a certain size ... drugs, inhibit specific Metastatic dissemination to surgically inaccessible sites is the molecules implicated in tumor development and are typically less major cause of death in cancer patients. Targeted therapies, harmful

https://www.justice.gov/epstein/files/DataSet%209/EFTA01201684.pdf

EFTA01741615Set 10

2011-11-087p3,030w

Figure 1-8-11). Figure 1-8-10. Average viability 6 standard deviation of tumor morse From Robrnson> D. et al. Cryob&ogy 2001.43.4-10 EFTA_R1_00031721 EFTA01741616 ... experiments with human prostatic adenocarcinoma grown subcutaneously in nude mice. Prior to cryosurgery, the tumors of test mice were injected interstitially with AFP-l. In control mice, the tumors were ... Figure 1-8-13. Typical micrographs of the j b. Obtained from prostate cancer tumors that were injected with phosphate-buffered saline solution prior to freezing; ?c. ?Obtained from tumors

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01741615.pdf

EFTA00648468Set 9

2011-01-252p1,142w

provocative strategy of fighting cancer with cancer. Researchers at the Rogosin Institute are taking tumor cells from mice, encapsulating them in beads made from a seaweed- derived sugar called agarose ... dogs and cats stricken with cancer, the treatment substantially reduced the size of tumors. In some cases animals lived significantly longer than expected, according to two articles being published Tuesday ... study, scientists are testing whether cancer cells implanted into patients can signal the patients' tumors to stop growing, shrink or even die. View Full Image te-'1_,BEADS "This

https://www.justice.gov/epstein/files/DataSet%209/EFTA00648468.pdf

EFTA02022988Set 10

2011-01-252p1,190w

provocative strategy of fighting cancer with cancer. Researchers at the Rogosin Institute are taking tumor cells from mice, encapsulating them in beads made from a seaweed-derived sugar called agarose ... dogs and cats stricken with cancer, the treatment substantially reduced the size of tumors. In some cases animals lived significantly longer than expected, according to two articles being published Tuesday ... study, scientists are testing whether cancer cells implanted into patients can signal the patients' tumors to stop growing, shrink or even die. View Full Image 'NNNN. Cancer research is replete

https://www.justice.gov/epstein/files/DataSet%2010/EFTA02022988.pdf

EFTA00805732Set 9

drug wasn't slowing or stopping But this time was different. Clinical oncologist tumor growth. Everolimus seemed to be another bust. David Solit, director of developmental therapeutics Then there ... Sloan-Kettering, saw a new opportunity to explain trial with advanced metastatic cancer. Tumors had what happened by sequencing the whole genome of invaded deep into her abdomen, clouding ... years old. None of analyzing all 3 billion bases of the DNA from a tumor the standard bladder cancer drugs were working for would've been absurdly time-consuming

https://www.justice.gov/epstein/files/DataSet%209/EFTA00805732.pdf

EFTA01788084Set 10

2011-01-252p1,195w

provocative strategy of fighting cancer with cancer. Researchers at the Rogosin Institute are taking tumor cells from mice, encapsulating them in beads made from a seaweed-derived sugar called agarose ... dogs and cats stricken with cancer, the treatment substantially reduced the size of tumors. In some cases animals lived significantly longer than expected, according to two articles being published Tuesday ... study, scientists are testing whether cancer cells implanted into patients can signal the patients' tumors to stop growing, shrink or even die. View Full Image chttp://si.wsj.net/public/resources/images/PJ-AZ008_BEADS_D_2=110124201806.jpg> Cancer research

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01788084.pdf

EFTA00679004Set 9

2017-04-279p2,237w

Facebook. 2017 Awards Established Investigator Awards Single cell analysis and perturbation of the tumor-immune ecosystem: Seeks to use single cell sequencing techniques to identify tumor, tumor microenvironment and immune ... based biomarkers for melanoma diagnosis and prognostication: Aims to identify genetic alterations in melanoma tumors that correlate with outcome and develop a candidate algorithm that can distinguish low from high ... immunotherapy in melanoma: Will use PET imaging to visualize T cells directly killing tumor cells, which has potential to act as a biomarker of immunotherapy efficacy MRA Established Investigator Award

https://www.justice.gov/epstein/files/DataSet%209/EFTA00679004.pdf

EFTA00661250Set 9

2011-11-084p3,024w

Paru Chins Ulara-Selatan ke N 2008 rigor° 15.10. Average Wedgy° standard deviation of tumor morsels (expressed as optical density per 100 mg wet • Medal Emas: weight) Perlimpunan Pengobatan From ... with human prose: do adenocarcinoma grown subcutaneously in nude mix. Fria to cryosurgery. the tumors of test mice were injected interstitially with Aral. In control mice. the terrors were injected ... cancer tissue before (a) and after cryosurgery (Wand (a) b. Obtained from prostate cancer tumors that were injected with phosphateduffered seine solution prim to freezing: ?c.? °Waned from tumors that

https://www.justice.gov/epstein/files/DataSet%209/EFTA00661250.pdf

EFTA00506107Set 9

Ready to Infuse O (Day 15) og T-cells Target Autologous Blood Oncolytic Agent Tumor Activated to (vvDD) into And Release Express T-cell T-cells Agent To Tumor targeting ... tumor antigens NkG2D C Cell (48 hrs) Tumor Blood Vessels Tumor Eradication (4 - 8 hrs) DAC AR T C API IAL LLC EFTA00506144 ConcentRx A cell-based therapy platform that ... Juno) have unequivocally shown that combining an appropriate autologous immune cell with an appropriate tumor cell antigen can achieve a demonstrable oncolytic effect in humans. The ConcentRx technology platform further

https://www.justice.gov/epstein/files/DataSet%209/EFTA00506107.pdf

EFTA02295528Set 11

Infuse (Day 15) O ° 0 ° Th i 0§ Autologous T-cells Target Oncolytic Agent Tumor Blood (vvDD) into And Release Activated to T-cells Agent To Express T-cell targeting ... tumor Tumor Cell (48 antiaens NkG2D hrs) Blood Vessels Immune Cells Tumor Eradicatio (4 - 8 hrs) DACART CAPITAL LLC EFTA_R1_01138839 EFTA02295565 ConcentRx A cell-based therapy platform that ... Juno) have unequivocally shown that combining an appropriate autologous immune cell with an appropriate tumor cell antigen can achieve a demonstrable oncolytic effect in humans. The ConcentRx technology platform further

https://www.justice.gov/epstein/files/DataSet%2011/EFTA02295528.pdf

EFTA01199737Set 9

other genes [10. 11. 12. 13. 14 disease burden, but in most cases the tumor returns as a con- Recently. mathematical modeling and clinical data were used to sequence ... genetic composition of this resistant subpopu- cells would then expand during treatment, repopulate the tumor and lation. Using a novel approach of ordering the resistant subclones cause treatment failure. Similar ... subelones obtained from liquid biopsies of cells resistant to chemotherapy are present in a tumor of a certain size colorectal cancer patients treated with EGFR blockade. Our the- [16]. Later

https://www.justice.gov/epstein/files/DataSet%209/EFTA01199737.pdf

EFTA00625051Set 9

breast cancer should not use oral contraceptives because breast cancer is a hormone-sensitive tumor. Some studies suggest that oral contraceptive use has been associated with an increase ... Myocardial infarction • Cerebral hemorrhage • Cerebral thrombosis • Hypertension • Gallbladder disease • Hepatic adenomas or benign liver tumors There is evidence of an association between the following conditions and the use of oral ... pains), cancer of the breast or sex organs, jaundice, or malignant or benign liver tumors You should not take the pill if you are pregnant or have unexplained vaginal bleeding

https://www.justice.gov/epstein/files/DataSet%209/EFTA00625051.pdf

EFTA00901699Set 9

2011-01-033p1,188w

experimental test this year. Stray cancer cells in the blood mean that a tumor has spread or is likely to, many doctors believe. A test that can capture such cells ... test to try to predict what treatments would be best for each patient's tumor and find out quickly if they are working. "This is like a liquid biopsy" that ... provide enough of a sample to determine what genes or pathways control a tumor's growth. Or the sample may no longer be available by the time the patient gets

https://www.justice.gov/epstein/files/DataSet%209/EFTA00901699.pdf

EFTA02714314Set 11

filter out thousands of cancer cells for genetic analysis. CTC stands for "circulating tumor cells," which are found in the blood of anyone with metastatic cancer. Today, the sole Food ... them a key piece in designing personalized treatment. To date, most genetic analysis of tumors is done by way of a biopsy. The biopsy procedure, however, can be very difficult ... patient, especially if the tumor is in the bone, and is not possible for all cancers such as Leukemia, when tumors rarely form. Furthermore, a biopsy cannot EFTA

https://www.justice.gov/epstein/files/DataSet%2011/EFTA02714314.pdf

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Corpus: 1990-03-17 – 2025-12-01

July 2010

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Results by Dataset467 total

Set 8

4

Set 9

281

Set 10

141

Set 11

41