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from the cell body along the cytoskeletal conveyer belt powered by either dynein or kinesin (depending on whether retrograde or anterograde). These same conveyer belts bring materials to the cell ... illuminate fundamental aspects of the distribution mechanism. They use motors of one or more kinesin families, along with cytoplasmic dynein, to translocate along microtubules, and bidirectional movement may be coordinated ... through interaction between dynein and kinesin-1. Translocation along actin filaments is probably driven by myosin V, but the protein(s) that mediate docking with actin filaments remain unknown. Signaling