Epstein Files Search

EFTA00707641Set 9

2017-09-1024p6,911w

responsible for those functions - we should be able to reverse energy deficits by replacing mitochondria. • Mitochondrial pathology is the highest order issue in degenerative diseases (chronic) and stroke (acute). Both ... function and concentration of mitochondria is decreased thereby reducing cellular function at every level. The same is true in cardiac conditions. • Mitochondria are otherwise very motile and can be internalized ... materials to the cell body and also remove waste, including the damaged and dying mitochondria. • Mitochondrial transplantation trials have worked well in heart and liver. • Mitochondria can be transplanted from

https://www.justice.gov/epstein/files/DataSet%209/EFTA00707641.pdf

EFTA00611136Set 9

2013-12-1915p10,933w

Nair. 2010: Wallace et al., 2010). There is considerable debate, however, about why mitochondria' homeostasis is Ever since eukaryotes subsumed the bacterial disrupted in the first place. The original idea ... Hannan, that ancestor of mitochondria, the nuclear and mitochon- reactive oxygen species (ROS) from mitochondria are a primary drial genomes have had to closely coordinate their cause of aging (Harman ... there is a specific loss of mitochondrial, but not communication between the nucleus and mitochondria to form nuclear, encoded OXPHOS subunits. We trace the stoichiometric OXPHOS complexes. This is mediated

https://www.justice.gov/epstein/files/DataSet%209/EFTA00611136.pdf

EFTA00664863Set 9

2017-09-183p814w

thursday and friday. i will also go visit the scientists that harvest and inject mitochondria at harvard (hearts only). oxygen and energy are the two highest order system issues - nonspecific ... quickly. i think it can change the game big time in the neuro space. Mitochondria/ transplantation in the human brain Idea Mitochondrial transplantation is based on the delivery of isolated ... viable mitochondria to the target organ to restore bioenergetic function. I believe we can augment or replace mitochondria in the brain damaged by ischemia/aging/disease as a mechanism to enhance cellular

https://www.justice.gov/epstein/files/DataSet%209/EFTA00664863.pdf

EFTA00688175Set 9

2017-09-193p935w

thursday and friday. i will also go visit the scientists that harvest and inject mitochondria at harvard (hearts only). oxygen and energy are the two highest order system issues - nonspecific ... human brain Idea Mitochondrial transplantation is based on the delivery of isolated, viable mitochondria to the target organ to restore bioenergetic function. I believe we can augment or replace mitochondria ... other organs with similar bioenergetic demands. Cardiac trial results show that 10 min following mitochondria] transplantation myocardial function is significantly enhanced as compared to hearts receiving injection of respiration media

https://www.justice.gov/epstein/files/DataSet%209/EFTA00688175.pdf

EFTA01018509Set 9

2017-09-193p913w

thursday and friday. i will also go visit the scientists that harvest and inject mitochondria at harvard (hearts only). oxygen and energy are the two highest order system issues - nonspecific ... human brain Idea Mitochondrial transplantation is based on the delivery of isolated, viable mitochondria to the target organ to restore bioenergetic function. I believe we can augment or replace mitochondria ... other organs with similar bioenergetic demands. Cardiac trial results show that 10 min following mitochondria] transplantation myocardial function is significantly enhanced as compared to hearts receiving EFTA01018509 injection of respiration

https://www.justice.gov/epstein/files/DataSet%209/EFTA01018509.pdf

EFTA00688178Set 9

2017-09-193p928w

thursday and friday. i will also go visit the scientists that harvest and inject mitochondria at harvard (hearts only). oxygen and energy are the two highest order system issues - nonspecific ... human brain Idea Mitochondrial transplantation is based on the delivery of isolated, viable mitochondria to the target organ to restore bioenergetic function. I believe we can augment or replace mitochondria ... other organs with similar bioenergetic demands. Cardiac trial results show that 10 min following mitochondria] transplantation myocardial function is significantly enhanced as compared to hearts receiving injection of respiration media

https://www.justice.gov/epstein/files/DataSet%209/EFTA00688178.pdf

EFTA01018516Set 9

2017-09-193p917w

thursday and friday. i will also go visit the scientists that harvest and inject mitochondria at harvard (hearts only). oxygen and energy are the two highest order system issues - nonspecific ... human brain Idea Mitochondrial transplantation is based on the delivery of isolated, viable mitochondria to the target organ to restore bioenergetic function. I believe we can augment or replace mitochondria ... other organs with similar bioenergetic demands. Cardiac trial results show that 10 min following mitochondria) transplantation myocardial function is significantly enhanced as compared to hearts receiving EFTA01018516 injection of respiration

https://www.justice.gov/epstein/files/DataSet%209/EFTA01018516.pdf

EFTA00799222Set 9

73p4,210w

drug C drug HD control mice More functional mitochondria = more ATP = more repair = more neurons = better behavior http://info.noldus.comitopic/rats Observer was blinded to the experimental conditions ... Clin Invest. 2013; 123:5371-5388 EFTA00799271 What are mitochondria? What do they do? • Power producers, ATP ROS • Polluters; free radicals (ROS) . 0 r ATP • Detoxifiers (aldehydes) C (Fp./ • Building ... Coordinators of apoptosis http://www.immortalhumans.com/wp- content/uploads/feat_mitochondria_diag_zoom.jpg (program cell death) EFTA00799272 Why focus on mitochondria health for dementia treatment? The brain: • 2% of the body mass (1.5kG) • Consumes

https://www.justice.gov/epstein/files/DataSet%209/EFTA00799222.pdf

EFTA01122595Set 9

3p1,745w

mail: EFTA01122595 UNIVERSITY OF skid ALBERTA Division of Cardiology hypertension. He proposed that mitochondria (the regulators of metabolism) can integrate many diverse decisions and activate or supress cell death accordingly ... Paradoxically, while the mitochondria sustain life by generating the cell's fuel, at the same time they have the ability to activate cell death and kill their host cell. Gopi ... life" and "pro-death" mechanisms, according to availability of fuel, all orchestrated within mitochondria. His thesis included work that was published in at several prestigious journals. In the first

https://www.justice.gov/epstein/files/DataSet%209/EFTA01122595.pdf

EFTA01210275Set 9

2017-08-2819p2,797w

that longevity as measured by time isn't quite right Seems like within mitochondria there's a "clock" that has a similar predetermined set of actions or events that could ... that longevity as measured by time isn't quite right Seems like within mitochondria there's a "clock" that has a similar predetermined set of actions or events that could ... Sender: Participants: ), Self (jeeitunes@gmail.com ) I think the answer is in mitochondria Oxygen is just fuel. Pressure is just another condition. iMessage 2017-08-28 20:13:14 UTC 4] Sender

https://www.justice.gov/epstein/files/DataSet%209/EFTA01210275.pdf

EFTA00781551Set 9

2018-09-3018p2,434w

book iMessage 2018-09-30 18:48:40 Ula n Sender: Participants: ), Self ( jeeitunes@gmail.com ) Mitochondria probably the place where chemistry becomes biology iMessage ... Sender: Participants: ), Self ( e:jeeitunes@gmail.com ) Mitochondria probably the place where chemistry becomes biology iMessage 2018-09-30 18:48:40 UTC 1 Sender: ) Participants: ( ), Self ( e:jeeitunes@gmail.com ) Mitochondria probably ... jeeitunes@gmail.com ) There are only two ways you can make energy in any life form Mitochondria or fermented sugars iMessage 2018-09-30 18:49:45 (1110 r31 Sender: Participants: Nina

https://www.justice.gov/epstein/files/DataSet%209/EFTA00781551.pdf

EFTA00589347Set 9

2012-11-203p1,134w

currently no approved pharmaceutical treatment options. Both products act to prevent the death of mitochondria in damaged cells and the cascade of intracellular biochemical events that lead to secondary tissue ... damage following a traumatic injury. By protecting a cell's mitochondria NeuroVive's products ensure that energy production is preserved and a damaged cell's normal regenerative mechanisms ... cyclosporine which, by inhibiting cyclophilin D, prevents the disruption of the membrane of the mitochondria. Sihuan is a leading Chinese pharmaceutical company with the largest cardio-cerebral vascular drug franchise

https://www.justice.gov/epstein/files/DataSet%209/EFTA00589347.pdf

EFTA01113072Set 9

2012-11-203p1,137w

currently no approved pharmaceutical treatment options. Both products act to prevent the death of mitochondria in damaged cells and the cascade of intracellular biochemical events that lead to secondary tissue ... damage following a traumatic injury. By protecting a cell's mitochondria NeuroVive's products ensure that energy production is preserved and a damaged cell's normal regenerative mechanisms ... cyclosporine which, by inhibiting cyclophilin D, prevents the disruption of the membrane of the mitochondria. Sihuan is a leading Chinese pharmaceutical company with the largest cardio-cerebral vascular drug franchise

https://www.justice.gov/epstein/files/DataSet%209/EFTA01113072.pdf

EFTA00668688Set 9

2012-11-284p1,496w

currently no approved pharmaceutical treatment options. Both products act to prevent the death of mitochondria in damaged cells and the cascade of intracellular biochemical events that lead to secondary tissue ... damage following a traumatic injury. By protecting a cell's mitochondria NeuroVive's products ensure that energy production is preserved and a damaged cell's normal regenerative mechanisms ... cyclosporine which, by inhibiting cyclophilin D, prevents the disruption of the membrane of the mitochondria. Sihuan is a leading Chinese pharmaceutical company with the largest cardio-cerebral vascular drug franchise

https://www.justice.gov/epstein/files/DataSet%209/EFTA00668688.pdf

EFTA01620793Set 10

13p826w

EFTA01620793 Wanted to talk to you about some very technical science ... 1. Mitochondria and what to do next - specifically I think what plants do is exactly right. But I think ... works nicely in defining the full spectrum of diseases. Might even relate to mitochondria as a solution but the bigger mechanistic picture could be interesting and it's very simple ... brain surgeon in Virginia. He is fascinated by the idea of mitochondria. Super smart and Down to earth. He basically just reads and learns and invests

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01620793.pdf

EFTA01620806Set 10

11p647w

plant talk O 01:08:34 am Great 01:13:51 am 2018/04/01 Mitochondria... Looks like it works in spinal cord ischemia too. Brain for sure. Heading to Boston ... 177bp) POLGI V.,ild,lype rtTA GFP Bright field 03:15:39 pm EFTA01620811 Mitochondria O 03:15:39 pin Yay 03:28:10 pm We are working ... brain. A little harder. But did you see the NYT Story in heart mitochondria last week? 03:28:52 pin We will end up being right if we do exactly

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01620806.pdf

EFTA01620779Set 10

7p654w

continue to practice. This is for credibility and also enjoyment. 3. Want to pursue mitochondria idea. Will take 18 months max to prove and i don't have ... business? Needs to start somewhere but ultimately I believe like you do that mitochondria transplant from plants to humans might be feasible. 4. Seems like a great time ... discuss when you've got time 0 07:16:58 am lay out mitochondria] test program, if you believe. . women time will be short lived so getonthe bandwagon

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01620779.pdf

EFTA00516734Set 9

2018-09-2919p2,944w

Participants: ( ), Self ( e:jeeitunes@gmail.com ) In 1904, Friedrich Meves, made the first recorded observation of mitochondria in plants in cells of the white waterlily iMessage ... Participants: ( ), Self ( e:jeeitunes@gmail.com ) In 1904, Friedrich Meves, made the first recorded observation of mitochondria in plants in cells of the white waterlily iMessage ... Participants: ( ), Self ( e:jeeitunes@gmail.com ) In 1904, Friedrich Meves, made the first recorded observation of mitochondria in plants in cells of the white waterlily iMessage

https://www.justice.gov/epstein/files/DataSet%209/EFTA00516734.pdf

EFTA01977314Set 10

2012-11-1852p9,298w

chromosomes can be investigated in both men and women by studying the mitochondria! RNA we have derived in an unbroken chain from our line of female progenitors. It turns ... that there is much more variation in the mitochondria! RNA of Jewish women than in the Y chromosomal DNA of Jewish men. This is understood by Falk and Ostrer ... much greater than it was in Palestine three millennia ago. Y chromosomal DNA or mitochondria! RNA is used by anthropologists and historians EFTA R1 00463861 EFTA01977359 precisely because they

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01977314.pdf

EFTA01620704Set 10

8p841w

that longevity as measured by time isn't quite right Seems like within mitochondria there's a "clock" that has a similar predetermined set of actions or events that could ... know 08:12:45 pm I think the answer is in mitochondria Oxygen is just fuel. Pressure is just another condition. 08:13:17 pm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801852/ Sent ... interesting I want to slow down division time and reduce variation and damage to mitochondria 08:14:35 pm EFTA01620707 (Mine) 08:14:38 pm it is highly unlikely

https://www.justice.gov/epstein/files/DataSet%2010/EFTA01620704.pdf